Conjugated polymer nanoparticles for small interfering RNA delivery.
نویسندگان
چکیده
Loosely aggregated conjugated polymer nanoparticles (CPNs) were used as nontoxic and efficient small interfering RNA (siRNA) delivery vehicles with delivery visualization. A significant down regulation (94%) of a target gene was achieved by transfection of HeLa cells with the CPNs/siRNA complexes, supporting CPN as a promising siRNA delivery carrier.
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عنوان ژورنال:
- Chemical communications
دوره 47 29 شماره
صفحات -
تاریخ انتشار 2011